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Sleep Cycles In Early Fetus Revealed

April 14th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
After about seven months growing in the womb, a human fetus spends most of its time asleep. Its brain cycles back and forth between the frenzied activity of rapid eye movement (REM) sleep and the quiet resting state of non-REM sleep. But whether the brains of younger, immature fetuses cycle with sleep or are simply inactive has remained a mystery, until now. Tags:

Major Restless Legs Study Completes Enrollment With Support From MediciGlobal

April 1st, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
Successful and seamless completion of clinical trial enrollment requires careful forecasting of screened to randomized patients, market research, an effective recruitment strategy, and project management guided by real time metrics. MediciGlobal's President and CEO Liz Moench notes: "This is achievable when clinical trial sites are engaged and motivated to meet timelines. Tags:

Experts Unite To Create New Online Resource For Restless Legs Syndrome

March 20th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
The website Under the Covers of RLS (http://www.rlsunderthecovers.com) brings together leading medical experts in the field of Restless Legs Syndrome (RLS) who have undertaken to explain key facts and symptoms of this condition, which affects people's sleep pattern, their ability to perform tasks which require longer periods of immobility, and negatively impacts patients' quality of life. Tags:

Astellas And XenoPort Announce Positive Results From Phase 2 Trial Of ASP8825/XP13512 In Japan For Restless Legs Syndrome

March 4th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
Astellas Pharma Inc. (Astellas) and XenoPort, Inc. (NASDAQ:XNPT) announced preliminary top-line results from a Phase 2 clinical trial of ASP8825/XP13512 for the treatment of symptoms in moderate-to-severe primary restless legs syndrome (RLS) patients. The trial was conducted by Astellas in Japan. ASP8825/XP13512 demonstrated statistically significant improvements compared to placebo on the primary endpoint of the trial and was well tolerated. Tags:

Astellas And XenoPort Announce Positive Results From Phase 2 Trial Of ASP8825/XP13512 In Japan For Restless Legs Syndrome

March 4th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
Astellas Pharma Inc. (Astellas) and XenoPort, Inc. (NASDAQ:XNPT) announced preliminary top-line results from a Phase 2 clinical trial of ASP8825/XP13512 for the treatment of symptoms in moderate-to-severe primary restless legs syndrome (RLS) patients. The trial was conducted by Astellas in Japan. ASP8825/XP13512 demonstrated statistically significant improvements compared to placebo on the primary endpoint of the trial and was well tolerated. Tags:

Stages Of Sleep Have Distinct Influence On Process Of Learning And Memory

February 26th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
Research on the sleeping brain has revealed some fascinating stage-dependent interactions between areas involved in formation and storage of long term memories. The study, published by Cell Press in the February 26th issue of the journal Neuron, may also provide a framework for further understanding the role of sleep in memory. Mammalian sleep occurs in two discrete stages, slow wave sleep (SWS) and rapid eye movement (REM) sleep. Tags:

Evidence For Precise Communication Across Brain Areas During Sleep Discovered By Caltech Scientists

February 26th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
By listening in on the chatter between neurons in various parts of the brain, researchers from the California Institute of Technology (Caltech) have taken steps toward fully understanding just how memories are formed, transferred, and ultimately stored in the brain--and how that process varies throughout the various stages of sleep. Tags:

Stages Of Sleep Have Distinct Influence On Process Of Learning And Memory

February 26th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
Research on the sleeping brain has revealed some fascinating stage-dependent interactions between areas involved in formation and storage of long term memories. The study, published by Cell Press in the February 26th issue of the journal Neuron, may also provide a framework for further understanding the role of sleep in memory. Mammalian sleep occurs in two discrete stages, slow wave sleep (SWS) and rapid eye movement (REM) sleep. Tags:

Evidence For Precise Communication Across Brain Areas During Sleep Discovered By Caltech Scientists

February 26th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
By listening in on the chatter between neurons in various parts of the brain, researchers from the California Institute of Technology (Caltech) have taken steps toward fully understanding just how memories are formed, transferred, and ultimately stored in the brain--and how that process varies throughout the various stages of sleep. Tags:

News From The Journal Of Neuroscience 3-Feb-2009

February 4th, 2009 | No Comments | Posted in Medical Information, Neurology / Neuroscience
1. IRBP Is Required for Retinaldehyde Transport Minghao Jin, Songhua Li, Steven Nusinowitz, Marcia Lloyd, Jane Hu, Roxana A. Radu, Dean Bok, and Gabriel H. Travis In photoreceptors, absorption of a photon by an opsin-associated chromophore causes isomerization of 11-cis to all-trans retinaldehyde, which activates the opsin. Before the chromophore can absorb another photon, the all-trans isomer must be converted back to the 11-cis form. Tags:
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