Wakeful Resting Linked To Improved Memory

New research from the US shows that resting while awake appears to strengthen memory, revealing new insights into how forms of rest other than sleep, affect the memory consolidation process... Tags: Insomnia Sleeping problems Insomnia information Sleepin

Sounds Can Penetrate Deep Sleep And Enhance Associated Memories Upon Waking

They were in a deep sleep, yet sounds, such as a teakettle whistle and a cat's meow, somehow penetrated their slumber. The 25 sounds presented during the nap were reminders of earlier spatial learning, though the Northwestern University research participants were unaware of the sounds as they slept. Yet, upon waking, memory tests showed that spatial memories had changed. Tags: Insomnia Sleeping problems Insomnia information Sleepin

Researchers Find First Potential Pathogenic Mutation For Restless Legs Syndrome

An international team of researchers led by scientists at the Mayo Clinic campus in Florida have found what they believe is the first mutated gene linked to restless legs syndrome, a common neurologic disorder. The researchers, who reported the findings in the July 21 issue of Neurology, doubt that a large proportion of the millions of people who suffer from the syndrome have this mutated MEIS1 gene. Tags: Insomnia Sleeping problems Insomnia information Sleepin

No Increased Risk Of Treatment-Induced Augmentation In Restless Legs Syndrome Demonstrated In Long-Term Placebo-Controlled Study With Mirapexin/Sifrol

New data presented at the 61st Annual Meeting of the American Academy of Neurology (AAN), in Seattle, U.S.A. show that augmentation did not significantly differ in RLS patients treated with Mirapexin® /Sifrol® (pramipexole*) versus the group receiving placebo.1Augmentation, i.e. the worsening of RLS symptoms due to pharmacological treatment, has been frequently observed in patients treated with levodopa, a dopaminergic agent sometimes used to treat RLS. Tags: Insomnia Sleeping problems Insomnia information Sleepin

Sleep Cycles In Early Fetus Revealed

After about seven months growing in the womb, a human fetus spends most of its time asleep. Its brain cycles back and forth between the frenzied activity of rapid eye movement (REM) sleep and the quiet resting state of non-REM sleep. But whether the brains of younger, immature fetuses cycle with sleep or are simply inactive has remained a mystery, until now. Tags: Insomnia Sleeping problems Insomnia information Sleepin

Major Restless Legs Study Completes Enrollment With Support From MediciGlobal

Successful and seamless completion of clinical trial enrollment requires careful forecasting of screened to randomized patients, market research, an effective recruitment strategy, and project management guided by real time metrics. MediciGlobal's President and CEO Liz Moench notes: "This is achievable when clinical trial sites are engaged and motivated to meet timelines. Tags: Insomnia Sleeping problems Insomnia information Sleepin

Experts Unite To Create New Online Resource For Restless Legs Syndrome

The website Under the Covers of RLS (http://www.rlsunderthecovers.com) brings together leading medical experts in the field of Restless Legs Syndrome (RLS) who have undertaken to explain key facts and symptoms of this condition, which affects people's sleep pattern, their ability to perform tasks which require longer periods of immobility, and negatively impacts patients' quality of life. Tags: Insomnia Sleeping problems Insomnia information Sleepin

Astellas And XenoPort Announce Positive Results From Phase 2 Trial Of ASP8825/XP13512 In Japan For Restless Legs Syndrome

Astellas Pharma Inc. (Astellas) and XenoPort, Inc. (NASDAQ:XNPT) announced preliminary top-line results from a Phase 2 clinical trial of ASP8825/XP13512 for the treatment of symptoms in moderate-to-severe primary restless legs syndrome (RLS) patients. The trial was conducted by Astellas in Japan. ASP8825/XP13512 demonstrated statistically significant improvements compared to placebo on the primary endpoint of the trial and was well tolerated. Tags: Insomnia Sleeping problems Insomnia information Sleepin

Astellas And XenoPort Announce Positive Results From Phase 2 Trial Of ASP8825/XP13512 In Japan For Restless Legs Syndrome

Astellas Pharma Inc. (Astellas) and XenoPort, Inc. (NASDAQ:XNPT) announced preliminary top-line results from a Phase 2 clinical trial of ASP8825/XP13512 for the treatment of symptoms in moderate-to-severe primary restless legs syndrome (RLS) patients. The trial was conducted by Astellas in Japan. ASP8825/XP13512 demonstrated statistically significant improvements compared to placebo on the primary endpoint of the trial and was well tolerated. Tags: Insomnia Sleeping problems Insomnia information Sleepin

Stages Of Sleep Have Distinct Influence On Process Of Learning And Memory

Research on the sleeping brain has revealed some fascinating stage-dependent interactions between areas involved in formation and storage of long term memories. The study, published by Cell Press in the February 26th issue of the journal Neuron, may also provide a framework for further understanding the role of sleep in memory. Mammalian sleep occurs in two discrete stages, slow wave sleep (SWS) and rapid eye movement (REM) sleep. Tags: Insomnia Sleeping problems Insomnia information Sleepin